Preclinical Pathology Services for Medical Devices

Why Companies Choose NAMSA for Preclinical Pathology Research

20

Fully Equipped ORs and Cath Labs in US and Europe

1650

Medical Device Preclinical Projects Last Year

13

Board-Certified DaBT Toxicologists on Staff

17

Pathologists Located in the US and Europe

Get Clearer Answers With NAMSA’s Preclinical Pathology Research

Pathology plays a central role in preclinical development, revealing how devices interact with living tissue and identifying issues before clinical trials begin. Skilled pathologists can pinpoint early biological responses and uncover potential safety concerns that inform design or material changes long before human evaluation.

NAMSA’s pathology laboratories are built for precision and efficiency, supporting high study volumes while maintaining the rigorous standards expected in regulated research. Fully equipped histopathology and SEM/TEM laboratories allow detailed examination of tissue-device interactions across a wide range of preclinical applications.

Our pathology teams provide:

  • Gross necropsy oversight and expert interpretation of histopathology slides
  • Comprehensive reporting on device safety and tissue response
  • Advanced sectioning using paraffin, plastic thin microtomy, laser microtome systems, and plastic EXAKT ground sectioning

Each study is conducted by experienced histotechnicians under the supervision of board-certified pathologists. This approach ensures the accuracy and consistency needed to guide critical development decisions and prepare devices for clinical success.

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Want to learn more about our experience in medical device pathology and preclinical research?

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Advancing Medical Device Pathology Through Proven Expertise

We have been assisting medical device companies with biocompatibility testing, consulting and preclinical services since 1967.

Post-Mortem Exams

  • Large or small in vivo models
  • Evans blue staining
  • Ex-vivo perfusion fixation
  • Fluorogram guided tissue harvesting
  • In-situ perfusion fixation
  • Microdissection
  • Pharmacokinetic sampling
  • TTC in-situ and ex-vivo staining

Imaging

  • High-resolution radiography (Faxitron)
  • Micro-CT
  • Histomorphometry
  • Scanning electron microscopy (SEM)
  • Transmission electron microscopy (TEM)
  • Stereomicroscopy
NAMSA's State-of-the-Art Histology Laboratory

Immunohistochemistry (IHC) Services

NAMSA offers immunohistochemistry (IHC) services as part of our histopathology suite to pinpoint how specific proteins and cell markers respond to implanted devices or materials. Through selective antibody staining, IHC helps distinguish biological responses that traditional histology may not capture. These studies give researchers a sharper view of how implanted materials behave in living systems, allowing teams to interpret subtle tissue changes and refine device design with greater accuracy.

Other Preclinical Services That May Interest You

Modern medical device setup with blue-covered equipment and multiple monitors, representing NAMSA's preclinical services.

Preclinical Research

Blue-gloved hands using a pipette to work with pink laboratory tubes.

Non-GLP Studies

Scientist in a lab coat using a pipette in a laboratory setting.

GLP Preclinical Studies

Let’s Talk About Your Project

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